Publications by authors named "Maria J N Alves"

Article Synopsis
  • Exercise training was found to improve various health aspects in tumor-bearing rats with severe cancer cachexia, including running capability and muscle function, while also prolonging lifespan and reducing oxidative stress.
  • A specific protein, COPS2, was identified as significantly downregulated in the skeletal muscle of these cancer-afflicted rats, and exercise training helped normalize its levels.
  • The research suggests that COPS2 plays a crucial role in muscle cell response to cancer, and exercise could serve as a potential therapeutic approach to combat muscle wasting in cancer patients.
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Background Exercise training improves neurovascular control and functional capacity in heart failure (HF) patients. However, the influence of the aetiology on these benefits is unknown. We compared the effects of exercise training on neurovascular control and functional capacity in idiopathic, ischaemic and hypertensive HF patients.

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The objective of this study was to evaluate the effects of exercise training on plasma removal of a cholesterol-rich nanoemulsion (LDE) that mimics low-density lipoprotein (LDL) lipid structure and binds to LDL receptors. LDE-derived cholesteryl ester plasma kinetics was studied in 24 exercise-trained and 20 sedentary male subjects. LDE labeled with [(14)C]cholesteryl ester was injected intravenously, and plasma samples were collected over a 24-h period to determine radioisotope decay curves.

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