Publications by authors named "Maria J Maciel"

Article Synopsis
  • A 57-year-old man with a heart problem was taken to the ICU because he had serious blood clots.
  • He was treated with a special slow medicine called alteplase that helped dissolve the blood clots over two days.
  • After improving, he had heart surgery a month later, showing that this new treatment can be helpful for stubborn clots.
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Wolff-Parkinson-White (WPW) syndrome is the most common manifestation of ventricular pre-excitation syndrome and is mostly found in individuals with no structural heart disease. Although the risk of malignant arrhythmias is low, sudden cardiac death (SCD) as the first clinical manifestation of WPW syndrome is well documented, and atrial fibrillation (AF) with a rapid ventricular response is the main mechanism involved. Unfortunately, the signs of pre-excitation and arrhythmias are sometimes under-diagnosed and under-treated.

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Introduction: Since 2011, the European guidelines have included a specific low-density lipoprotein cholesterol (LDL-C) target, <70 mg/dl, for very high cardiovascular risk (CVR) patients. However, registries have shown unsatisfactory results in obtaining this level of adequate lipid control.

Objectives: To assess temporal trends in the use of lipid-lowering therapy (LLT) and attainment of adequate control in very high CVR patients since 2011.

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Aims: Assessing reversibility of pulmonary vascular changes through vasoreactivity testing (VRT) optimizes end-stage heart failure patient selection for heart transplant. All efforts should be made to unload the left ventricle and reduce pulmonary vascular resistance to effectively exclude irreversible pulmonary hypertension.

Methods And Results: We reviewed our centre's cardiac transplant registry database (2009-2017) for VRT and compared haemodynamic responses with 40 ppm inhaled NO (n = 14), 14-17 μg inhaled iloprost (n = 7), and 24 h 0.

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Objective: To assess the clinical impact of a cardiac rehabilitation program in an older population.

Methods: This is a retrospective analysis of 731 coronary patients who attended phase 2 of a cardiac rehabilitation program between January 2009 and December 2016. We compared the response to the program of older (≥65 years) and younger (<65 years) patients, analyzing changes in metabolic profile (including body mass index, waist circumference and lipid profile), exercise capacity, cardiac autonomic regulation parameters (such as chronotropic index and resting heart rate), and health-related quality of life scores.

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We report a case of temporary pacemaker lead malposition in the left ventricle crossing the interventricular septum (IVS). The majority of described cases occur due to a patent foramen ovale and are frequently incidental findings. A course across the IVS is rarely found and this complication with temporary leads is not even reported in the literature.

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Article Synopsis
  • The study focuses on the timely treatment of patients with ST-segment elevation myocardial infarction (STEMI) and high-risk non-ST-elevation acute coronary syndromes (NSTE-ACS) in Portugal, aiming to analyze delays in care based on diagnosis and risk profile.
  • It involved 939 patients admitted to cardiology departments, revealing that significant delays in medical contact were most prevalent among high-risk NSTE-ACS patients (57.7%) compared to STEMI patients (43.3%).
  • Factors contributing to delays included patients using their own transportation, difficulty in recognizing heart symptoms, and systemic issues like being admitted to hospitals without specific intervention capabilities, particularly on weekends.
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Purpose: To study the role of left ventricle systolic function in cardiac rehabilitation program (CRP) response in stage B heart failure patients.

Methods: A retrospective analysis was completed of 691 patients with previous myocardial infarction that underwent a CRP, classified in 3 groups: preserved ejection fraction (pEF), mid-range ejection fraction (mrEF), and reduced ejection fraction (rEF). We compared the response to CRP analyzing the relative changes of estimated cardiorespiratory fitness (CRFe), resting heart rate (HR), and chronotropic index (CI).

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Purpose: To evaluate the response of patients with obesity to a cardiac rehabilitation program (CRP), compared with patients without obesity.

Methods: We performed a retrospective analysis of 731 patients who completed phase II of a CRP after an acute coronary syndrome. The response to the CRP was assessed using the relative changes in exercise capacity (EC), resting heart rate (HR), and chronotropic index (CI).

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Introduction: This study examined the efficacy of a brief inpatient psychoeducational intervention on knowledge about acute coronary syndromes (ACS), control of risk factors, and adaptive health habits and lifestyle. The intervention was intended to facilitate rehabilitation after ACS and its short- and medium-term impact was assessed.

Methods: One hundred and twenty-one patients with ACS, admitted to a central cardiology unit in Portugal, were randomized to an experimental group (EG, n=65) or a control group (CG, n=56).

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Introduction: Papillary fibroelastoma (PFE) is a rare primary benign tumor of cardiac origin that predominantly affects the cardiac valves. Although most patients are asymptomatic, serious complications may result given their propensity for embolization. Advances in imaging technology have enabled earlier detection and more accurate characterization of these tumors.

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Article Synopsis
  • After fixing a heart problem called tetralogy of Fallot, some adults may develop a widening of a part of the aorta (the main blood vessel) years later.
  • A study looked at 78 adults, finding that 11.5% had this widening, and it was more common in older males and those with bigger heart sizes.
  • The researchers suggest that checking the aorta should be a regular part of heart scans for these patients to catch any problems early, especially for those with specific risk factors.
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Article Synopsis
  • Researchers studied adults who had surgery for a heart condition called tetralogy of Fallot (TOF) to see if their arteries, especially the aorta, were bigger or stiffer.
  • They looked at 126 TOF patients and compared them to 63 healthy people, finding that many TOF patients had an enlarged aorta.
  • They discovered that being male was a strong predictor of having a larger aorta, and it's important for these patients to be checked regularly to avoid future health problems.
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Introduction And Objectives: Despite increased awareness of sex disparities in care and outcomes of acute myocardial infarction (AMI), there appears to have been no consistent attenuation of these differences over the last decade. We investigated differences by sex in management and 30-day mortality using the European Society of Cardiology Acute Cardiovascular Care Association quality indicators (QIs) for AMI.

Methods: Proportions and standard errors of the 20 Acute Cardiovascular Care Association QIs were calculated for 771 patients with AMI who were admitted to the cardiology departments of 2 tertiary hospitals in Portugal between August 2013 and December 2014.

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Background: Late after tetralogy of Fallot (TOF) repair some patients exhibit aortic dilatation and stiffness. Noninvasive assessment of aortic stiffness could contribute to understand this aortopathy and may be important in risk stratification for major aortic event.

Methods: We included prospectively 82 adults after TOF repair and 41 age- and sex-matched normal controls.

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Background: Heart failure with preserved ejection fraction (HFpEF) is now well recognized but the identification of patients with HFpEF can be challenging. We aimed to evaluate the performance of tissue Doppler imaging indexes and left atrial size in HFpEF diagnosis.

Methods And Results: We designed a case-control study in which cases are patients with acute heart failure and controls are age-matched and sex-matched patients with multiple cardiovascular risk factors admitted to hospital because of stroke.

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Objectives: Prompt diagnosis of acute coronary syndrome (ACS) remains a challenge, with presenting symptoms affecting the diagnosis algorithm and, consequently, management and outcomes. This study aimed to identify sex differences in presenting symptoms of ACS.

Design: Data were collected within a prospective cohort study (EPIHeart).

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Objectives: To estimate cardiac rehabilitation (CR) referral and participation rates among patients with acute coronary syndrome (ACS) and to identify their determinants, in two Portuguese regions.

Design: Prospective cohort study.

Setting: Patients consecutively admitted to the cardiology department of two hospitals, one in the district of Porto and one in the north-east region (NER) of Portugal, were enrolled in the EPIHeart cohort and then followed up for 6 months.

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