Local and distant recurrence of the chromophobe renal cell carcinoma.

Introduction: There is still limited knowledgeabout surveillance and optimal management for patientswith recurrent chromophobe renal cell carcinoma. OBJECTIVE: Describe our experience in the diagnosis andmanagement in recurrent chromophobe renal cell carcinoma.

Material And Method: Review of medical records ofpatients with chromophobe renal cell carcinoma, selectingthose cases that developed recurrence.

[Bladder leiomyomas.].

Unlabelled: Bladder leiomyomas are rare benign tumors; their common presentation are irritative and obstructive urinary symptoms. The treatment is complete surgical resection.

Objective: To present our experience in the diagnosis and the treatment of bladder leiomyoma.

Adrenal ganglioneuroma.

Objective: To present one case of adrenal ganglioneuroma incidentally diagnosed in an adult.

Methods/results: 44-year-old woman with a 2.3 cm incidentaloma in the left adrenal gland diagnosed by CT scan.

Supernumerary testicle: case report and bibliographic review.

Objective: We report a case of supernumerary testis, a rare anomaly with only around 100 cases reported in the literature.

Methods: We describe the case of a 26-year-old man who consulted for a left paratesticular tumor. Physical examination and ultrasound showed a 2-cm nodular lesion over the left epididymis.

Neuroendocrine carcinoma of the urinary bladder. 15-year retrospective analysis.

Objectives: Neuroendocrine tumors (NET) are cancers found in the bronchopulmonary tract, where they were first described in 1926. The tumors are associated with poor prognosis due to their high metastatic potency even after radical treatments associated with other neo- or adjuvant therapies. NET of the urinary bladder is a rare tumor and accounts for 0.

Role of CYP1B1 gene polymorphisms in bladder cancer susceptibility.

Purpose: CYP1B1 activates procarcinogens in some human tissues, including the urinary tract. Changes related to genetic polymorphisms are a known risk factor for cancer. We analyzed the association between CYP1B1 sequence variations and bladder cancer.

Vaginal metastasis of a clear renal cell carcinoma.

Objective: Remember that kidney cancer is a disease whose incidence is increasing due to increased use of additional imaging tests, which is changing the way of diagnosis, making the classic clinical syndrome synonymous with advanced illness.

Methods: We report the case of a patient with a right renal tumor with renal vein involvement that in the natural course of the disease showed a vaginal metastasis of clear renal cell carcinoma, which was treated with surgical excision.

Results: This case is a clear example of how unpredictable is the clinical evolution of this disease and how little we know about the way of dissemination.

GSTT1, GSTM1, and CYP1B1 gene polymorphisms and susceptibility to sporadic renal cell cancer.

Purpose: To estimate the prevalence and importance of GSTT1, GSTM1, and CYP1B1 genotypes in renal cell carcinoma (RCC), and to identify their value as a prognostic factor.

Materials And Methods: Cross-sectional study of a group of patients diagnosed with RCC (n = 133) and a control group (n = 208) with benign conditions and no history of tumor. Controls were selected by cumulative samples and mixed pairing.

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.

Unlabelled: What's known on the subject? and What does the study add? Bladder cancer susceptibility may be determined by genetic differences in the activity of glutathione S-transferases, enzymes that regulate the conversion of exogenous carcinogens to excretable hydrophilic metabolites by glutathione conjugation. The discrepancy of results regarding the association of common genetic polymorphisms and complex diseases such as cancer has raised scepticism in this area of research. Although the evidence generally supports the implication of GSTM1 and GSTT1 polymorphisms in bladder cancer, there is still some debate, with some studies in favour and some against.

Metastasis to the tunica vaginalis testis from a primary mucinous tumor of the cecum.

Objectives: We review the literature about secondary testicular tumors.

Methods: We present the case of a patient with a metastatic mucus-secreting testicular tumor who presented in the emergency room with symptoms of acute scrotum 10 months after surgery for a mixed tumor of the cecum. This type of tumor is rare, and the treatment of choice is orchiectomy; nevertheless, the prognosis of such metastasis remains poor.

Primary retroperitoneal tumors: review of our 10-year case series.

Objectives: To investigate our case series of patients with primary retroperitoneal tumors over the past 10 years, analyzing clinical symptoms, diagnostic tests, tumor pathology, surgical data, concomitant cancer treatments, recurrence and survival rates.

Methods: Retrospective analysis of 37 patients with primary retroperitoneal tumors diagnosed at our hospital over the past 10 years.

Results: Computed tomography (CT) was the imaging technique used most often and the most accurate.

[Spermatic cord sarcomas: current status and report of four cases].

Objective: To study and review spermatic cord sarcomas, including symptoms, diagnosis, and treatment.

Methods/results: We review the Spanish and international literature and report 4 new cases: 2 patients with well-differentiated spermatic cord liposarcomas (1 treated by simple tumorectomy), 1 patient with liposarcomatous degeneration of a previously excised atypical lipoma, and 1 patient operated for a malignant retroperitoneal fibrous histiocytoma with subsequent local recurrence in the paratesticular region.

Conclusions: Spermatic cord sarcomas are rare entities that usually appear as painless paratesticular mass.

[Impact of surgical treatment of female stress urinary incontinence on the quality of life of patients].

Objectives: To evaluate the quality of life of patients with stress urinary incontinence (SUI) operated in the Department of Urology at the Complejo Hospitalario Universitario in Albacete (CHUA).

Methods: Between November 2001 and December 2005, 126 patients with SUI have completed a questionnaire in our centre, before and after undergoing surgery with sling techniques. The questionnaire was the King's Health Questionnaire (KHQ), which is a specific instrument for the measurement of quality of life in patients with urinary incontinence.

[Retroorbital metastasis in the initial diagnosis of prostate cancer].

Objective: To describe one case of advanced prostate cancer first presenting with binocular diplopia due to retroorbital metastasis.

Methods: We present the case of a 54-year-old patient with the diagnosis of disseminated prostate cancer treated by complete androgen blockade.

Results: After the start of hormonal treatment, the patient initially improved although survival was limited.

[Bellini duct carcinoma: report of two cases].

Objective: We report two cases of collecting duct carcinoma that were diagnosed in our hospital in a six-month period.

Methods/results: The first case was a 75years-old woman showing in CT scan a mass in the left kidney which infiltrated perinephric fat. The second case was a 72-years-old that showed in a CT scan a right renal pelvis lesion, involving inferior vena cava and renal vein.

[Ambulatory surgery in a urology department. Analysis of the period 2003-2006].

Objectives: When talking about day surgery we have to differentiate between minor and major ambulatory surgery. Ambulatory surgery enables the patient to stay in the hospital not more than a few hours, showing similar safety and efficacy than conventional surgery. The objective of this paper is to evaluate the results of an ambulatory surgery program.

[Current status of the diagnosis and treatment of Leydig cell testicular tumor. Report of two cases].

Objectives: To review the current diagnosis and treatment of Leydig cell testicular tumors, with special attention to conservative treatment.

Methods: We report two cases of Leydig cell tumor in young adults, diagnosed two years after the appearance of bilateral gynecomastia as first clinical symptom.

Results: One year and eight months after orchyectomy, respectively, clinical symptoms completely disappear in the first case and significantly improved in the second.

Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: a long-term study.

Objective: To determine the prognostic value of p53 gene mutations and P53 overexpression for predicting the incidence of recurrence, progression and long-term survival of patients with transitional cell carcinoma (TCC) of the bladder.

Methods: Prospective cohort study with 94 consecutive patients diagnosed and treated for TCC. DNA was obtained from tumor tissue to perform PCR-SSCP of p53 exons 5-9, with automatic sequencing of any mutated samples.

Implications of mismatch repair genes hMLH1 and hMSH2 in patients with sporadic renal cell carcinoma.

Objectives: To analyse the implications of DNA mismatch repair genes hMLH1 and hMSH2 in sporadic renal cell carcinoma (RCC).

Materials And Methods: Specimens of tumour and healthy renal tissue were collected from 89 patients treated for sporadic RCC. Another 95 blood samples taken from individuals with no history of cancer were also analysed.

Sensitivity and specificity of p53 protein detection by immunohistochemistry in patients with urothelial bladder carcinoma.

Objective: To analyze the correlation between the genotypic and phenotypic patterns of p53 in patients with transitional cell carcinoma (TCC) of the urinary bladder.

Materials And Methods: Cross-sectional study of 73 patients diagnosed with TCC. DNA was obtained from the tumor tissue to perform polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) of exons 5-9 of the p53 gene, with automatic sequencing done on any mutated samples.

[Late lymph node metastasis in renal cell carcinoma. Case report].

Objective: To report one case of late metastasis of a clear cell carcinoma treated by radical surgery.

Methods/results: Patient with history of radical nephrectomy and lymphadenectomy six years before presenting with regional lymph node metastasis in a followup diagnostic test. After treatment with immunotherapy, stopped because of intolerance, surgery of the metastatic lymph node mass was decided.

[Voiding symptoms changes after vaginal sling surgery for female stress urinary incontinence].

Objectives: To evaluate the changes in voiding symptoms in female patients with stress urinary incontinence (SUI) undergoing transvaginal sling techniques over a five-year period in the Department of Urology at the University Hospital of Albacete.

Methods: Between November 2001 and December 2005 126 patients with SUI (mean age 57.09 years; 36-78) underwent transvaginal sling techniques (Sling in Fast, TVK TOT).

Isolated testicular polyarteritis nodosa.

Isolated polyarteritis nodosa is a rare condition that may be triggered by local exposure to certain agents capable of provoking local immunostimulation without a systemic immune reaction. Isolated polyarteritis nodosa in the testes presents similar histologic characteristics as those of systemic inflammation, although infarcted areas in the testis are more common in generalized polyarteritis nodosa. Definitive diagnosis requires histologic study.