Publications by authors named "Maria Izarbe Merino-Casallo"
Study of Cellular Aging in a Cohort of Patients with Heart Failure.
Bularca Elena Merino-Casallo María Izarbe Olivera-González Susana Menao-Guillén Sebastián Sierra-Monzón José Luis
High Blood Press Cardiovasc Prev
January 2021
Article Synopsis
- Cellular senescence and fibrosis are connected to heart failure (HF) and related to telomere length (TL).
- The study aimed to analyze TL in peripheral blood mononuclear cells (PBMCs) from 20 HF patients (ages 51-77) compared to 20 healthy controls using real-time PCR.
- Results showed that TL was significantly shorter in HF patients (mean 1327) than in controls (mean 1286), while no significant correlations were found with age, gender, or clinical parameters, indicating TL shortening is independent of these factors.