High-dose-rate brachytherapy (interventional radiotherapy) in lip carcinoma with rigid needles: a simple technique with excellent results.

Lip carcinoma has been treated for years with low-dose-rate (LDR) brachytherapy, achieving local control greater than 90%. Comparison between LDR and high-dose-rate (HDR) showed that they are equivalently efficient in local control, but HDR results in fewer complications. Interstitial implant of rigid needles or plastic tubes (interventional radiotherapy) is the current standard.

Long-term results with custom-linked iodine-125 seeds and real-time brachytherapy in low- and intermediate-risk prostate cancer.

Purpose: Brachytherapy (BT) with iodine-125 (I) seeds is effective in low- and intermediate-risk prostate carcinoma, with fewer side effects compared to other techniques, but relapses increase in long-term. In the present paper, 10-year biochemical relapse-free survival (BRFS) results are presented.

Material And Methods: Between 2007 and 2016, 706 patients were treated with real-time technique using Bard-ProLink™ system.

Should high-dose-rate brachytherapy boost be used in early nasopharyngeal carcinomas?

Background: Radiation with or without chemotherapy is the main treatment of nasopharyngeal carcinomas (NPC). Local recurrence is difficult to manage. Local control is dose-dependent.

Can invasive breast carcinoma with close or positive margins be managed without a new surgery?

We present the long-term outcome (FU 127 months) of a prospective study with 248 breast cancer patients with close or positive surgical margin, treated with 50 Gy whole breast irradiation plus high-dose-rate boost, 3 × 4.4 Gy. Actuarial breast failure at 10/15 years was 6.

High-dose-rate interstitial brachytherapy boost in inoperable locally advanced tongue carcinoma.

Purpose: Locally advanced tongue carcinomas (LATCs) in inoperable lesions are managed with external beam radiation therapy (EBRT) and chemotherapy. In our institution, the boost to the gross tumor volume is delivered with high-dose-rate brachytherapy (HDR-BT) after EBRT. We review the outcome of these patients when HDR-BT is added as a boost.

High dose rate brachytherapy in early stage squamous-cell carcinoma of the lip.

Introduction And Goals: To analyze the results obtained after treatment of early stage (T1-T2) squamous cell carcinoma of the lip with high dose rate brachytherapy and evaluate the efficacy of this treatment in both local and regional control.

Materials And Methods: Retrospective analysis of the treatments performed at our department from March 1999 to March 2013 with high dose rate brachytherapy with rigid needles. We included 68 patients, 63 men and 5 women; 37 patients (54.

Comparison of permanent (125)I seeds implants with two different techniques in 500 cases of prostate cancer.

Purpose: To perform a comparative study of 500 consecutive (125)I seeds implants for intracapsular prostate carcinoma with two techniques differing in terms of both strand implantation and planning.

Material And Methods: From 2002 to 2007 we performed 250 implants with fixed stranded seeds (RapidStrand™) and a preplanning system and from 2007 to 2010, 250 with real-time and ProLink™ system. Mean age was 68 and 66, respectively, median PSA (prostate-specific antigen) 7.

High-dose-rate brachytherapy boost effect on local tumor control in young women with breast cancer.

Purpose: To evaluate the local control rate and complications of a single fraction of high-dose-rate brachytherapy (HDR BT) boost in women aged 45 yeas and younger after breast-conserving therapy.

Methods And Materials: Between 1999 and 2007, 167 patients between the ages of 26 and 45 years old (72 were 40 years old or younger), with stages T1 to T2 invasive breast cancer with disease-free margin status of at least 5 mm after breast-conserving surgery received 46 to 50 Gy whole-breast irradiation plus a 7-Gy HDR-BT boost ("fast boost"). An axillary dissection was performed in 72.

From low-dose-rate to high-dose-rate brachytherapy in lip carcinoma: Equivalent results but fewer complications.

Purpose: To compare the use of high-dose-rate (HDR) brachytherapy (BT) in patients with lip carcinoma with a former series previously treated with low-dose-rate (LDR) BT.

Methods And Materials: Ninety-nine patients treated with LDR-BT were compared with 104 patients treated with HDR-BT. Distribution by stage was 53.

Treatment of facial cutaneous carcinoma with high-dose rate contact brachytherapy with customized molds.

Background: The main treatment given for initial stage facial epitheliomas is surgery, although there are alternatives. We present our results with Ir-192 high-dose rate (HDR) contact brachytherapy.

Methods And Materials: Fifty-one epitheliomas, with a mean size of 1.

Efficacy of high-dose-rate interstitial brachytherapy in patients with oral tongue carcinoma.

Purpose: To evaluate the results of high-dose-rate (HDR)-interstitial brachytherapy (ISBT) in oral tongue carcinomas.

Methods And Materials: Between September 1999 and August 2007, 50 patients were treated for oral tongue carcinoma with HDR-ISBT. The patient's mean age was 58 years.