Publications by authors named "Maria Isabel Rodriguez-Naranjo"
Dual liquid-liquid extraction followed by LC-MS/MS method for the simultaneous quantification of melatonin, cortisol, triiodothyronine, thyroxine and testosterone levels in serum: Applications to a photoperiod study in rats.
J Chromatogr B Analyt Technol Biomed Life Sci
February 2019
Article Synopsis
- - The hypothalamic-pituitary (HP) axes influence the thyroid, adrenal glands, and gonads, and their changes are linked to various diseases, highlighting the need for analyzing hormones like melatonin, cortisol, T3, T4, and testosterone for better therapeutic diagnosis.
- - A validated analytical method was developed for simultaneously measuring these hormones in serum using liquid-liquid extractions followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), ensuring high accuracy and cost-effectiveness.
- - The method demonstrated excellent linearity, recovery rates, and precision, and was effectively used to investigate the effects of light exposure on hormone levels in rats, confirming its suitability for studying HP axis modulation.
Impairment of lysophospholipid metabolism in obesity: altered plasma profile and desensitization to the modulatory properties of n-3 polyunsaturated fatty acids in a randomized controlled trial.
Am J Clin Nutr
August 2016
Background: Plasma lysophospholipids have emerged as signaling molecules with important effects on inflammation, insulin resistance, and fatty liver disease, each of which is linked closely to obesity. Dietary n-3 (ω-3) polyunsaturated fatty acids (PUFAs) may be able to improve these conditions.
Objective: The objective of this study was to assess the response of plasma lysophospholipids to obesity, n-3 PUFA consumption, and a high-fat meal challenge to better understand the role of lysophospholipid metabolism in the progression of obesity-related disorders.
Melatonin is a bioactive compound that is present in wine because it is contained in vinification grapes and synthesized by yeast during alcoholic fermentation. The purpose of this study was to determine the capacity of various Saccharomyces strains to form melatonin during its growth and alcoholic fermentation. A selection of yeasts including six S.
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