Pharmacokinetic Study of Biotransformation Products from an Anxiolytic Fraction of Tilia americana.

An anxiolytic fraction of standardized in tiliroside, rutin, quercitrin, quercetin glucoside, and kaempferol was obtained. After oral administration of the fraction, the above-mentioned flavonoids were not detected in plasma over 24 h. However, and hydroxyphenylacetic acid and dihydroxyphenylacetic acid (-HPAA, -HPAA and DOPAC) were monitored.