Publications by authors named "Maria Isabel Gonzalez Fernandez"
Background: To assess the psychosocial impact of moderate-severe juvenile idiopathic arthritis (JIA) on patients and their families, among those who had been treated with at least one anti-tumor necrosis factor (anti-TNF-α), according to routine clinical practice in Spain.
Patients And Methods: A 24-month observational, multicentric, cross-sectional and retrospective study was performed. Children diagnosed with JIA were enrolled at three tertiary-care Spanish hospitals.
The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Castilian Spanish language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients.
View Article and Find Full Text PDFClinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis).
Pediatr Rheumatol Online J
November 2015
Article Synopsis
- The study focuses on granulomatosis with polyangiitis (GPA) in children, analyzing data from 56 pediatric patients diagnosed before age 18.
- Most of the patients were female (68%) and Caucasian (82%), with a median diagnosis age of around 11.7 years and an average diagnosis delay of 4.2 months.
- Clinical signs were predominantly seen in the ears, nose, throat, and respiratory system, with a notable percentage of patients testing positive for ANCA-PR3 and presenting with haematuria/proteinuria, showing different patterns of organ involvement compared to adults.
Objective: To evaluate whether early treatment with methotrexate (MTX) prevents the onset of uveitis in children with juvenile idiopathic arthritis.
Study Design: The clinical charts of all consecutive patients seen between January 2002 and February 2011 who had a disease duration <1 year at first visit and had received a stable management for at least 2 years with or without MTX were reviewed. Patients who were given systemic medications other than MTX (except nonsteroidal anti-inflammatory drugs) were excluded.
Objective: To investigate the outcome and predicting factors of multiple intraarticular corticosteroid (IAC) injections in children with juvenile idiopathic arthritis (JIA).
Methods: The clinical charts of patients who received their first IAC injection in ≥3 joints between January 2002 and December 2011 were reviewed. The corticosteroid used was triamcinolone hexacetonide for large joints and methylprednisolone acetate for small or difficult to access joints.