Creation of knowledge-based planning models intended for large scale distribution: Minimizing the effect of outlier plans.

Knowledge-based planning (KBP) can be used to estimate dose-volume histograms (DVHs) of organs at risk (OAR) using models. The task of model creation, however, can result in estimates with differing accuracy; particularly when outlier plans are not properly addressed. This work used RapidPlan to create models for the prostate and head and neck intended for large-scale distribution.