Publications by authors named "Maria Ines Zimiani"
Article Synopsis
- The study investigates how altered sensorimotor gating is measured in patients with early bipolar disorder and schizophrenia using both muscular and neural responses during Prepulse Inhibition (PPI) tests.
- Findings show that both neural and muscular PPI were significantly reduced in schizophrenia patients, while bipolar disorder patients displayed neural PPI deficits but not muscular.
- The results imply that using combined measures could provide new insights into sensory processing issues unique to each disorder.
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Front Neurosci
September 2018
Article Synopsis
- The paper discusses a new method for assessing prepulse inhibition (PPI) using both electromyography (EMG) and electroencephalography (EEG) to better understand sensorimotor gating in humans.
- The study involved 22 healthy participants and combined recordings of muscular responses (using EMG) and brain activity (using EEG), specifically looking at event-related potentials.
- This approach successfully reduced muscle-related artifacts in the EEG signals and demonstrated that the new method could effectively evaluate neural PPI within a crucial time frame (100-200 ms) that other tests miss.
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