Publications by authors named "Maria Ines Carmona-Lopez"
Article Synopsis
- Human papillomavirus (HPV) is the leading cause of cervical cancer, significantly impacting women in Chile, where cervical cancer is a major health risk for those aged 20-44.
- This study tested a less invasive urine-based method for HPV detection using PCR, comparing it to the traditional cervical brush approach.
- Results showed both methods effectively detected carcinogenic HPV types, with the urine approach providing a promising alternative to improve screening, especially for women avoiding pelvic exams.
Introduction: classical studies have compared the glycemia with the nutritional status in both children and adults; however studies that consider also somatotype are unknown.
Objective: associating the somatotype and nutritional status with the glycemic level of students of Pedagogy in Physical Education (PPE).
Methods: the sample included 40 subjects, divided between 13 women and 27 men.
Introduction: A study was conducted on histological patterns and biomolecular changes in Goitrogen-induced experimental rat thyroid tumors. The link between the histological types observed and N-ras, B-raf, and PI3KCA gene mutations widely reported in human thyroid cancers was explored.
Material And Methods: An analysis was done on paraffin-embedded tumor tissue sections from Wistar rats receiving 1% potassium perchlorate (KClO(4)) added to the ad libitum drinking-water supply over an 18-month period.
It is widely held that solid cell nests (SCN) of the thyroid are ultimobranchial body remnants. SCNs are composed of main cells and C cells. It has been suggested that main cells might be pluripotent cells contributing to the histogenesis of C cells and follicular cells, as well as to the formation of certain thyroid tumors.
View Article and Find Full Text PDFOxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved by increasing intracellular reactive oxygen species (ROS) and/or by depleting the protective antioxidant machinery of tumor cells. We focused our investigations on the antitumoral potential of amitriptyline in three human tumor cell lines: H460 (lung cancer), HeLa (cervical cancer), and HepG2 (hepatoma); comparing the cytotoxic effect of amitriptyline with three commonly used chemotherapeutic drugs: camptothecin, doxorubicin, and methotrexate. We evaluated apoptosis, ROS production, mitochondrial mass and activity, and antioxidant defenses of tumor cells.
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