Liver iron concentration quantification by MRI: are recommended protocols accurate enough for clinical practice?

Objective: To assess the accuracy of quantification of liver iron concentration (LIC) by MRI using the Rennes University (URennes) algorithm.

Methods: In the overall study period 1999-2006 the LIC in 171 patients was calculated with the URennes model and the results were compared with LIC measured by liver biopsy.

Results: The biopsy showed that 107 patients had no overload, 38 moderate overload and 26 high overload.