Publications by authors named "Maria I Carrion"

Article Synopsis
  • The ECT Working Group of the Catalan Society of Psychiatry conducted a survey in 2022 across 20 public hospitals in Catalonia to examine variations in electroconvulsive therapy (ECT) practices.
  • The survey included 50 questions covering organization, technique, therapeutic strategies, and resource management, identifying major depression as the primary reason for ECT in 80% of centers.
  • Key findings highlighted consistent ECT application rates, a growing complexity in procedures emphasizing quality and safety, and the need for improvements in resource management and team training.
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Introduction: Research data show the impact of the endocannabinoid system on psychosis through its neurotransmission homeostatic functions. However, the effect of the endocannabinoid system genetic variability on the relationship between cannabis use and psychosis has been unexplored, even less in first-episode patients. Here, through a case-only design, we investigated the effect of cannabis use and the genetic variability of endocannabinoid receptors on clinical and cognitive outcomes in first-episode psychosis (FEP) patients.

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The role of both cannabis use and genetic background has been shown in the risk for psychosis. However, the effect of the interplay between cannabis and variability at the endocannabinoid receptor genes on the neurobiological underpinnings of psychosis remains inconclusive. Through a case-only design, including patients with a first-episode of psychosis (n = 40) classified as cannabis users (50%) and non-users (50%), we aimed to evaluate the interaction between cannabis use and common genetic variants at the endocannabinoid receptor genes on brain activity.

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Article Synopsis
  • The Neuritin 1 gene is being studied as a potential genetic factor in schizophrenia due to its links to the risk for the disorder and cognitive performance.
  • The research involved genetic analyses of families with early-onset and adult-onset schizophrenia, alongside a control group, to see how Neuritin 1 affects the age of onset and brain activity.
  • Findings indicated specific genetic haplotypes are linked to early-onset schizophrenia and associated with poorer performance in working memory tasks, revealing a connection between genetic markers and brain function in those with the disorder.
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Vitamin D deficiency has been linked with schizophrenia. We aimed to determine whether patients with a first episode of psychosis (FEP) had lower vitamin D levels compared with controls considering their final diagnosis. We conducted a cross-sectional study determining 25-hydroxyvitamin D blood levels.

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