Publications by authors named "Maria Huertas Vaquero"
Objective: The study of the evolution of certain biomarkers in patients with persistent detection of SARS-CoV-2 could determine the profile of the pathology that these patients may suffer. The objective of this study was to describe the evolution of different laboratory markers in patients with persistent detection of SARS-CoV-2, and determining these parameters were into reference values.
Methods: Patients were divided into two groups: the control group (G0) included patients with a positive direct test for SARS-CoV-2 followed by 2 negative, while the problem group (G1) included patients with at least 3 consecutive positive tests.
Article Synopsis
- The study aimed to investigate the connection between the initial PCR cycle threshold (CT) values of COVID-19 patients and the persistence of the virus in their nasopharyngeal tract.
- It involved a retrospective analysis of patients with positive SARS-CoV-2 PCR results, comparing two groups: those who tested negative after two positive results (control group) and those who remained positive for at least three tests (problem group).
- Results showed that patients in the control group had higher mean CT values (30.8) compared to the problem group (21.5), indicating that lower CT values are linked to prolonged virus positivity, irrespective of symptoms or radiological findings.
Objective: To determine the risk and prognostic factors for Clostridioides difficile infection (CDI).
Patients And Methods: Prospective, case-control study with 61 cases and 64 controls, aged ≥2 years with diarrhoea, carried out in Castilla-La Mancha Health Care Area for 14 months. The diagnosis was made by immunochromatography technics (glutamate dehydrogenase and toxin A/B), confirming discordant cases by isothermal amplification.
Utility of multiplex PCR syndromic panel for respiratory infections in the diagnosis of acute bacterial meningitis.
Enferm Infecc Microbiol Clin (Engl Ed)
November 2021
Utility of multiplex PCR syndromic panel for respiratory infections in the diagnosis of acute bacterial meningitis.
Enferm Infecc Microbiol Clin (Engl Ed)
December 2020
Interhospital dissemination of KPC-3 producing-Klebsiella pneumoniae ST512. Detection by MALDI-TOF.
Enferm Infecc Microbiol Clin (Engl Ed)
February 2021
Introduction/objective: To describe an outbreak of KPC-3-producing Klebsiella pneumoniae (KPN) and determine the diagnostic efficacy of MALDI-TOF in its detection.
Methods: Retrospective study of the KPC-3-KPN isolated in 2 hospitals in Ciudad Real. The peak at 11,109kDa±15 was sought in the KPN spectra provided by MALDI-TOF.
Trend and seasonality of community-acquired Escherichia coli antimicrobial resistance and its dynamic relationship with antimicrobial use assessed by ARIMA models.
Enferm Infecc Microbiol Clin (Engl Ed)
October 2018
Introduction: We studied the trend and seasonality of community-acquired Escherichia coli resistance and quantified its correlation with the previous use of certain antibiotics.
Methods: A time series study of resistant community-acquired E. coli isolates and their association with antibiotic use was conducted in a Primary Health Care Area from 2008 to 2012.
Introduction/objective: To perform a cost-effectiveness analysis of a molecular biology technique for the diagnosis of tuberculosis compared to the classical diagnostic alternative.
Methods: A cost-effectiveness analysis was performed to evaluate the theoretical implementation of a molecular biology method including two alternative techniques for early detection of Mycobacterium tuberculosis Complex, and resistance to rifampicin (alternative1: one determination in selected patients; alternative2: two determinations in all the patients). Both alternatives were compared with the usual procedure for microbiological diagnosis of tuberculosis (staining and microbiological culture), and was accomplished on 1,972 patients in the period in 2008-2012.
Introduction: Endogenous endophthalmitis (EE) is a prevalent but serious disease. Our aim was to describe cases of EE, with emphasis in the risk factors and the improvement of the prognosis.
Methods: A review of EE cases was done between 1996-2011 in a secondary care hospital in Spain.
[Economic impact of the introduction of a technique for early detection of Mycobacterium tuberculosis Complex in clinical samples in a Spanish hospital].
Rev Esp Salud Publica
March 2014
Background: Tuberculosis (TB) remains an important public health problem worldwide. Our objective was to estimate the economic and health care impact of the introduction of an early diagnosis tecnique of TB, the Xpert MTB/RIF® assay (Xpert).
Methods: The savings was estimated on the basis of reduction in the time of TB hospitalization at avoid the false-negative (FN) and false-positive (FP) TB cases diagnosed by auramine staining that could have been detected by Xpert between 2008-2012 in our hospital.