Two new naphthoquinones, 7-hydroxy-2--methyldunniol () and 7-methoxy-2--methyldunniol () were isolated from the tubers of (Seem.) G. Nicholson (Gesneriaceae).
View Article and Find Full Text PDF(Dilleniaceae) has been used in folk medicine to treat inflammation and pain; however, studies evaluating its toxicity potential, as well as its effects on anxiety and depression, are scarce. This study investigated the toxicological profile of an ethanolic extract from leaves of (EEDd), and its effects on anxiety and depression models in mice. Male and female mice received either a single dose (500, 1000 or 2000 mg/kg) or repeated doses (75, 150 or 300 mg/kg) of EEDd by oral gavage.
View Article and Find Full Text PDFThe increase in the manufacture of craft beers follows the boost in the consumption of this beverage. Meanwhile, brewers face a drawback with beer aging, its flavor's change. The addition of compounds that overcome this downside is one alternative used by brewers.
View Article and Find Full Text PDFEthnopharmacological Relevance: In the State of Mato Grosso do Sul, the watery sap of Doliocarpus dentatus is used to alleviate thirst, and the leaves of this species are used to relieve pain and swelling associated with inflammatory processes.
Aim Of The Study: This study aimed to analyze the compounds of the leaves from the aqueous extract of D. dentatus (EADd) and evaluate its toxicogenetic and pain relief effects in animal models.
Chemical investigation of the extracts of the fruits from resulted in the isolation of six known compounds identified by NMR and comparison with literature data (2',4'-dihydroxy-5'-methyl-6'-methoxychalcone (), 2',4'-dihydroxy-3',5'-dimethyl-6'-methoxychalcone (), 2'-hydroxy-3'-methyl-4',6'-dimethoxychalcone (), 2',6'-dihydroxy-3'-methyl-4'-methoxychalcone (), 5-hydroxy-7-methoxy-8-methylflavanone () and 7-hydroxy-5-methoxy-6-methylflavanone ()). The considerable antioxidant capacity of the extracts was demonstrated by ORAC-FL and DPPH tests. The antiproliferative assay of the extracts and was done , against many different cancer cell lines besides a healthy one.
View Article and Find Full Text PDFBackground: Infusions of aerial parts of Artemisia vulgaris L. (Asteraceae) are used in herbal medicine to treat several disorders, including hepatosis.
Purpose: Evaluation of in vivo hepatoprotective effects of A.
A new naphthoquinone, 7,8-dimethoxydunnione (1), was isolated from Sinningia leucotricha (Hoehne) Moore tubers, together with four known compounds: 7- hydroxy-t-dunnione (2), 6-methoxy-7-hydroxy-a-dunnione (3), presilphiperfolan-9-ol (4), and betulinic acid (5). All compounds were identified by spectroscopic and mass spectrometric techniques and comparison with literature data. Compounds 2-5 are being reported for the first time in S.
View Article and Find Full Text PDFTwo new hydronaphthoquinones, aggregatins E and F (1 and 2, resp.) were isolated from the tubers of Sinningia aggregata (Ker-Gawl.) Wiehler (Gesneriaceae), along with twelve known compounds aggregatin D (3), tectoquinone (4), 1-hydroxy-2-methylanthraquinone (5), icosyl ferulate (6), pustuline (7), 1,6-dihydroxy-2-methylanthranquinone (8), 6-hydroxy-2-methylanthraquinone (9), 7-hydroxy-2-methylanthraquinone (10), tyrosol (11), halleridone (12), calceolarioside B (13), and cornoside (14).
View Article and Find Full Text PDFA new naphthoquinone, 6-methoxy-7-hydroxy-a-dunnione (1), along with four known compounds (2, 4, 10, and 11) were isolated from Sinningia canescens (Mart.) Wiehler tubers, while S. warmingii (Hiern.
View Article and Find Full Text PDFChem Biodivers
December 2012
The family Gesneriaceae comprises ca. 150 genera and 3000 species, distributed in the tropics around the world. It is constituted of herbs, lianas, or shrubs, frequently with ornamental potential, due to the beauty of their flowers.
View Article and Find Full Text PDFThree new aromatic epsilon-lactones, aggregatins A (1), B (2), and C (3), a new naphthoquinone derivative, aggregatin D (4), and three known anthraquinones, 2-methylanthraquinone, 7-methoxy-2-methylanthraquinone, and 7-hydroxy-2-methylanthraquinone, were isolated from the tubers of Sinningia aggregata (Gesneriaceae). Compounds 1 and 4 and the anthraquinones showed marginal antimicrobial activity.
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