Publications by authors named "Maria Helena Cruz Santos"
Canavalia ensiformis lectin induced oxidative stress mediate both toxicity and genotoxicity in Drosophila melanogaster.
Int J Biol Macromol
December 2022
Mannose/glucose-binding lectin from Canavalia ensiformis seeds (Concanavalin A - ConA) has several biological applications, such as mitogenic and antitumor activity. However, most of the mechanisms involved in the in vivo toxicity of ConA are not well known. In this study, the Drosophila melanogaster model was used to assess the toxicity and genotoxicity of different concentrations of native ConA (4.
View Article and Find Full Text PDFLectins ConA and ConM extracted from Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.) DC inhibit planktonic Candida albicans and Candida tropicalis.
Arch Microbiol
May 2022
Lectins participate in the defense against microorganisms and in signaling the damage caused by pathogens to the cell surface and/or intracellular in plants. This study aims to analyze the antifungal potential of lectins extracted from seeds of Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.
View Article and Find Full Text PDFIs the orofacial antinociceptive effect of lectins intrinsically related to their specificity to monosaccharides?
Int J Biol Macromol
October 2020
Article Synopsis
- Lectins are proteins that have potential biological benefits, particularly in reducing inflammation and pain, which was the focus of a study evaluating their effects on zebrafish.
- The study specifically examined three plant lectins (DVL, VML, and PPL) to see if they could alleviate pain from menthol and capsaicin when injected into the fish, with the PPL lectin showing significant antinociceptive effects only against capsaicin.
- The findings suggested that not all lectins have the same pain-relieving properties, and the way they bind to carbohydrates may influence their effectiveness in reducing pain.