Publications by authors named "Maria H Coenen"
Article Synopsis
- The study aimed to assess the reproducibility of primary data and the correctness of pooled sensitivity and specificity estimates in diagnostic meta-analyses, specifically comparing coronary computed tomography angiography to invasive coronary angiography.
- Out of 38 meta-analyses reviewed, 82% had reproducible contingency tables, but only 15 published them, and 74% yielded comparable recalculated sensitivities and specificities using the original pooling methods.
- The research highlighted a need for better data sharing practices and more consistent application of recommended statistical methods, as overall improvements in these areas have been marginal over time.*
Objective: To determine whether coronary computed tomography angiography (CTA) should be performed in patients with any clinical probability of coronary artery disease (CAD), and whether the diagnostic performance differs between subgroups of patients.
Design: Prospectively designed meta-analysis of individual patient data from prospective diagnostic accuracy studies.
Data Sources: Medline, Embase, and Web of Science for published studies.