Publications by authors named "Maria Guadalupe Olguin-Garcia"
Background And Aims: The treatment of recalcitrant facial flat warts has always been challenging for dermatologists. The pain related to the application of the different treatments, side effects and costs are determining factors in the choice of therapy. To date, it is known that oral isotretinoin administered at a dose of 0.
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- FAM20C is an important protein kinase involved in bone development and phosphate regulation, and its deficiency leads to Raine syndrome (RNS), characterized by bone abnormalities and low phosphate levels.
- RNS can cause various neurological issues, including developmental delays and seizures, but little is understood about how FAM20C affects brain proteins.
- A study utilized various databases to analyze FAM20C targets, revealing that genes highly expressed in the brain are linked to cholesterol transport and neuronal functions, which may provide insights into the neurologic features of RNS.
is a gene coding for a protein kinase that targets S-X-E/pS motifs on different phosphoproteins belonging to diverse tissues. Pathogenic variants of are responsible for Raine syndrome (RS), initially described as a lethal and congenital osteosclerotic dysplasia characterized by generalized atherosclerosis with periosteal bone formation, characteristic facial dysmorphisms and intracerebral calcifications. The aim of this review is to give an overview of targets and variants of FAM20C as well as RS aspects.
View Article and Find Full Text PDFThis systematic review of measurement instruments for vitiligo outcomes included validation articles published from 2011 to May 2018. According to the PRISMA statement, the search was carried out in EMBASE (via OvidSP); MEDLINE (via OvidSP and PubMed). The COSMIN taxonomy will be used to define the measurement properties.
View Article and Find Full Text PDFUnlabelled: Abstract Background: Recalcitrant facial flat warts are caused by human papillomavirus and may persist for years despite treatment. Isotretinoin has demonstrated benefits in the treatment of recalcitrant, genital and common warts, but placebo-controlled trials have not been performed.
Objective: To determine whether isotretinoin is safe and effective for recalcitrant facial flat warts.