Publications by authors named "Maria Grazia Ruvoletto"
Int J Mol Med
January 2010
Article Synopsis
- SCCA1 is overexpressed in certain tumors and may play a role in inhibiting cell death and promoting cell growth, especially in liver cells after surgery.
- In a study with transgenic mice expressing human SCCA1, researchers found that these mice had a significantly higher liver weight and proliferation activity after partial liver removal compared to wild-type mice.
- Interestingly, the cytokine interleukin-6 showed a strong sex-dependent increase in transgenic female mice, suggesting different responses to liver regeneration based on sex and SCCA1 expression.
