Growth hormone and hematopoiesis: A retrospective analysis on a large cohort of children with growth hormone deficiency.

Objective: Few large-scale studies regarding the impact of GH deficiency (GHD) on hematopoiesis in children have been reported. Our aim was to investigate hematopoiesis indices in a large cohort of GHD children at diagnosis and during GH treatment (GHT) and any correlation with hormonal parameters.

Design: Clinical and biochemical data of children with idiopathic GHD at diagnosis and annually up to 36 months of GHT were retrospectively evaluated.

The metabolic outcomes of growth hormone treatment in children are gender specific.

Objective: To evaluate the impact of gender on the clinical and metabolic parameters in prepubertal growth hormone deficiency (GHD) children at diagnosis and during GH treatment (GHT).

Design: The data of 105 prepubertal children (61 males, 44 females, mean age 6.8 ± 0.