Exploring the Contribution of Proximal Family Risk Factors on DNA Methylation in Children with a History of Maltreatment: A Preliminary Study.

The cumulative effects of proximal family risk factors have been associated with a high number of adverse outcomes in childhood maltreatment, and DNA methylation of the serotonin transporter gene () has been associated with child maltreatment. However, the relationships between proximal family risk factors and methylation remains unexplored. We examined the association among cumulative family risk factors, maltreatment experiences and DNA methylation in the gene in a sample of 33 child victims of maltreatment.