Publications by authors named "Maria Gladysheva"
Tumor cells of acute lymphoblastic leukemia (ALL) may have various genetic abnormalities. Some of them lead to a complete loss of certain genes. Our aim was to reveal biallelic deletions of genes in Ph-negative T-ALL.
View Article and Find Full Text PDFThe landscape of chromosomal aberrations in the tumor cells of the patients with B-ALL is diverse and can influence the outcome of the disease. Molecular karyotyping at the onset of the disease using chromosomal microarray (CMA) is advisable to identify additional molecular factors associated with the prognosis of the disease. Molecular karyotyping data for 36 patients with Ph-negative B-ALL who received therapy according to the ALL-2016 protocol are presented.
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- Photoinduced linkage isomers (PLIs) of the nitro-ligand were created and analyzed in a square planar structure of the complex salts, utilizing various structural (XRD) and spectroscopic (IR, UV-vis) methods to identify different photoinduced isomers generated through irradiation.
- Irradiation at low temperatures (10-80 K) produced both -ONO and -ONO isomers, while heating to higher temperatures (up to 150 K) favored the formation of only -ONO isomers, suggesting that intermolecular interactions, particularly with water, affect their structural arrangement.
- The study also outlined a detailed thermal decay process for -ONO isomers through two steps to revert to NO, determining kinetic parameters and decay temperatures