Morphological and biological properties of silica nanoparticles for CRTC3-siRNA delivery and downregulation of the RGS2 expression in preadipocytes.

The aim of this study was to characterize the morphological properties of amorphous silica nanoparticles (SiO NPs), their cytotoxicity and intracellular location within Human Osteoblasts (HOB). Additionally, SiO NPs were explored for their effectivity as carriers of CRTC3-siRNA on Human Preadipocytes (HPAd), and thus downregulate RGS2 gene expression. SiO NPs were synthesized using the method of Stöber at 45 °C, 56 °C, and 62 °C.

Role of iron carbonyls in the inhibition of oxygen activation for the oxidation of CO catalyzed by iron oxide-supported gold.

Iron oxide-supported gold samples were prepared by co-precipitation from HAuCl(4) and Fe(NO(3))(3). The activities of the samples as CO oxidation catalysts were tested without thermal treatment and following treatments in flows of He and O(2) at various temperatures. It was found that the untreated samples and those treated in a flow of He at 150 °C were more active than samples that had been treated at 400 °C in either a flow of O(2) or of He.