Publications by authors named "Maria Fredrika Norrbin"
Article Synopsis
- The study explores the "One Strain Many Compounds" (OSMAC) approach to discover bioactive compounds by introducing stress factors, focusing on how grazing pressure impacts the metabolome of marine diatoms when co-cultured with zooplankton.
- In large-scale bioreactor experiments, the researchers found that diatom extracts exhibited higher bioactivity in assays against human lung cells when under grazing stress from zooplankton, although it did not significantly impact biofilm formation or bacterial growth.
- The analysis of metabolic profiles revealed distinct differences between the diatom's chemical outputs in monoculture versus co-culture, suggesting that grazing stress alters diatom biochemistry and could enhance the OSM
