Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium.

Natural substances of plant origin exert health beneficiary efficacy due to the content of various phytochemicals. Significant anticancer abilities of natural compounds are mediated via various processes such as regulation of a cell's epigenome. The potential antineoplastic activity of plant natural substances mediated by their action on posttranslational histone modifications (PHMs) is currently a highly evaluated area of cancer research.

Malaria in hyperendemic region of Uganda has seasonal variations and is associated with low mortality.

Objective: Majority of malaria cases in hyper-endemic areas have seasonal variations. The aim of this short research note is to refer and assess seasonal variability and mortality of malaria in Ngogwe in southeast Uganda in 2011/2012 season.

Methods: We analyzed clinical records of patients admitted to Buikwe-Ngogwe Hospital in the period from July 1, 2011 to August 25, 2012 to assess seasonality of malaria.

Gene polymorphisms in bladder cancer.

In Europe, cancer of the bladder is the fourth most common cancer among men, accounting for 7% of total cancers. In the USA, bladder cancer is the fifth most common cancer in men and seventh in women. This disease is three times more common in men than in women.