Publications by authors named "Maria Fernanda Vergara-Martinez"
In Brief: Social insect queens display both extraordinary longevity and fertility. In this point of view, we describe their distinctive traits that make them useful models for reproductive longevity, holding implications for human health discoveries.
Abstract: Social insects present an extraordinary opportunity as models for reproductive longevity because they challenge the conventional patterns of aging and reproduction seen in other model organisms.
The V-type H-ATPase is targeted in antidiuretic hormone control of the Malpighian "renal" tubules.
Proc Natl Acad Sci U S A
December 2023
Article Synopsis
- Mosquito Malpighian tubules (MTs) secrete substances driven by V-type H-ATPase (VA), which is influenced by diuretic hormones and inhibited by the neurohormone CAPA.
- Research shows that CAPA inhibits secretion by reducing VA activity through a NOS/cGMP/PKG signaling pathway, leading to changes in the distribution of VA protein complexes.
- This study enhances our understanding of the hormonal regulation of MTs, highlighting the importance of VA in maintaining hydromineral balance after a blood meal.