Publications by authors named "Maria Fernanda Martinez Salazar"

Physical activity (PA) levels, as well as symptoms of anxiety and depression, can affect adherence to antiretroviral therapy (ART) impacting people's health. This study aimed to evaluate the association between PA levels, clinical symptoms of anxiety and depression, and adherence to ART in people living with HIV (PLHIV). A cross-sectional study, including 125 PLHIV was conducted.

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Article Synopsis
  • MIS-C is a serious inflammatory condition that can occur in children 2 to 4 weeks after infection with SARS-CoV-2, characterized by inflammation and heart issues.
  • Despite being recognized for over two years, effective treatments for MIS-C are still being studied.
  • The review explores the potential of natural compounds that have antioxidant and anti-inflammatory properties as possible treatments to mitigate hyperinflammation associated with MIS-C.
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Human immunodeficiency virus (HIV) infection has continued to be the subject of study since its discovery nearly 40 years ago. Significant advances in research and intake of antiretroviral therapy (ART) have slowed the progression and appearance of the disease symptoms and the incidence of concomitant diseases, which are the leading cause of death in HIV+ persons. However, the prolongation of ART is closely related to chronic degenerative diseases and pathologies caused by oxidative stress (OS) and alterations in lipid metabolism (increased cholesterol levels), both of which are conditions of ART.

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Metabolic syndrome (MetS) has increased worldwide, and since 2012, prevalence of obesity, hypertension, diabetes, and dyslipidemia has increased in Mexico. To assess the prevalence of MetS, and its relationship with sociodemographic and lifestyle factors among Mexican adults. Analytical cross-sectional study nationally representative, carried out on Mexican adults (≥20-year-old adults of both sexes;  = 4595).

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Objective: To analyse the most frequent self-reported adverse reactions (ARs), the durability and the causes of antiretrovirals (ARVs) regimens change, concomitant treatments and drug interactions related to the use of ARVs in a group of people living with HIV in Cuernavaca, Morelos, Mexico.

Materials And Methods: Cross-sectional study conducted in a clinic specialising in HIV 'CAPASITS-Cuernavaca' in Mexico from February to June 2015. People who wanted to participate were given a questionnaire on demographic characteristics, adherence, concomitant treatments and ARs.

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Background: The serum paraoxonase-1 (PON1) associated to HDL presents two common polymorphisms in the positions 192 and 55. These polymorphisms are considered determinant of the capacity of HDL to protect LDL from their oxidative modification. In this context, the PON1 genotype has been associated with cardiovascular diseases, including stroke.

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Article Synopsis
  • The study investigates the relationship between certain enzymes (BuChE and PON1) and the nutritional and lipid profiles of children in rural Mexico, focusing on the risk factors associated with obesity and metabolic disorders.
  • Out of 97 children assessed, 34.4% were identified as overweight or obese, with findings showing these groups had higher levels of BuChE, cholesterol, and triglycerides compared to thinner or normally weighted peers.
  • Genetic analysis revealed that specific polymorphisms of the PON1 enzyme were common among the children, potentially influencing lipid levels and disease predisposition.
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Background: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities including insulin resistance, dyslipidemia, high blood pressure, and abdominal adiposity. Obese patients develop leptin resistance, and an increased waist circumference (WC) due to deposition of abdominal fat. The aim of this study was to evaluate the association between circulating leptin levels and MetS among sample adult Mexican workers.

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Article Synopsis
  • The study investigated the link between the L55M and Q192R genetic variations in the paraoxonase (PON1) enzyme and obesity among 127 Mexican adults aged 20-56.
  • Results showed that although arylesterase and paraoxonase activity levels were similar in obese and normal-weight individuals, the obese group had higher blood pressure, triglycerides, cholesterol, glucose, and insulin levels, while having lower HDL-C levels.
  • A significant finding was that the homozygous L genotype of the PON1-L55M polymorphism was more frequent in the obese group, suggesting a potential genetic association with obesity.
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