Publications by authors named "Maria Farrell"

Article Synopsis
  • The study evaluated the safety and effectiveness of using allodepleted donor T cells (ADTs) to enhance immune recovery in patients following matched unrelated donor (MUD) stem cell transplants, particularly after treatment with alemtuzumab for hematological cancers.
  • Results showed a trend toward higher CD3+ T-cell counts at 4 months for those receiving ADTs compared to the control group, but the difference was not statistically significant, and a few patients achieved normal T-cell levels.
  • While ADTs were deemed safe, the method's limited effect on T-cell reconstitution suggests it might be more beneficial in cases that involve more aggressive T-cell depletion.
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Breast cancer is the most common cancer in women, accounting for nearly 30% of all female cancers. Breast cancer is the second leading cause of cancer mortality in women in the US. During the last two decades, the benefits of early detection, early intervention, and postoperative treatment have resulted in decreased breast cancer mortality in the US general population.

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