Immunogenic potential and neutralizing ability of a heterologous version of the most abundant three-finger toxin from the coral snake .

is a coral snake of public health concern in Colombia. Its venom is mainly composed of three-finger toxins (3FTxs), Mipartoxin-1 being the most abundant protein partially responsible for its lethal effect. In this work, we present the production of Mipartoxin-1 in a recombinant form and evaluate its immunogenic potential.

Heterologous Expression and Immunogenic Potential of the Most Abundant Phospholipase A from Coral Snake to Develop Antivenoms.

is a coral snake of clinic interest in Colombia. Its venom is mainly composed of phospholipases A being MdumPLA the most abundant protein. Nevertheless, species produce a low quantity of venom, which makes it difficult to produce anticoral antivenoms.

A non-commercial approach for the generation of transgenic Leishmania tarentolae and its application in antileishmanial drug discovery.

Leishmaniasis is a parasitic infection caused by several species of the genus Leishmania that is considered as a neglected disease. Drug development process requires a robust and updated high-throughput technology to the evaluation of candidate compounds that imply the manipulation of the pathogenic species of the parasite in the laboratory. Therefore, it is restricted to trained personal and level II biosafety environments.