Protective effects of a grape-supplemented diet in a mouse model of retinal degeneration.

Objective: Retinal degenerations are a class of devastating blinding diseases that are characterized by photoreceptor dysfunction and death. In this study, we tested whether grape consumption, in the form of freeze-dried grape powder (FDGP), improves photoreceptor survival in a mouse model of retinal degeneration.

Methods: Retinal degeneration was induced in mice by acute oxidative stress using subretinal injection of paraquat.