Publications by authors named "Maria Emilia Santos Pereira Ramos"
Evaluation of mutagenic effects of formocresol: detection of DNA-protein cross-links and micronucleus in mouse bone marrow.
Maria Emília Santos Pereira Ramos Bruno Coêlho Cavalcanti Letícia Veras Costa Lotufo Manoel Odorico de Moraes Eneida de Moraes Marcílio Cerqueira
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
March 2008
Objective: The genotoxic potential of formocresol was assessed by comet assay on human peripheral blood lymphocytes and in vivo micronucleus in mice.
Study Design: Peripheral blood lymphocytes, obtained from healthy donors, were exposed directly with different dilutions of formocresol for 45 minutes at 37 degrees C. To verify the possibility of formocresol to induce DNA-protein cross-links, treated lymphocytes were incubated with proteinase K.