Evidence of brain metabolism redistribution from neocortex to primitive brain structures in early acute COVID-19 respiratory syndrome.

Background: Neuropsychiatric sequelae of COVID-19 have been widely documented in patients with severe neurological symptoms during the chronic or subacute phase of the disease. However, it remains unclear whether subclinical changes in brain metabolism can occur early in the acute phase of the disease. The aim of this study was to identify and quantify changes in brain metabolism in patients hospitalized for acute respiratory syndrome due to COVID-19 with no or mild neurological symptoms.

Head-to-head comparison of [Ga]Ga-PSMA-11 and [F]FDG PET/CT in multiple myeloma.

Purpose: The aim of this study was to compare [F]FDG and [Ga]Ga-PSMA-11 PET/CT image findings in patients with multiple myeloma (MM).

Methods: Twenty consecutive patients with symptomatic biopsy-proven MM were submitted to whole body [F]FDG and [Ga]Ga-PSMA-11 PET/CT with a time interval of 1-8 days between procedures. All lesions were counted and had their maximum SUV (SUVmax) measured.

Knee radiosynovectomy with Sm-hydroxyapatite compared to Y-hydroxyapatite: initial results of a prospective trial.

Introduction: Radiosynovectomy (RS) with Y-hydroxyapatite (Y-HyA) aims to control knee hemarthrosis in hemophiliac patients to prevent secondary arthropathy. However, knee RS using Sm-hydroxyapatite (Sm-HyA) is considered less suitable due to the lower average soft tissue range and energy of Sm for large joints, such as the knees.

Purpose: The objective of this investigation was to assess the efficacy and safety of knee RS with Sm-HyA, compared to Y-HyA.