Publications by authors named "Maria Elena Lamanna"
Article Synopsis
- COVID-19 can lead to acute respiratory distress syndrome, requiring ICU admission and invasive ventilation, which increases the risk of ventilator-associated pneumonia (VAP) in these patients.
- A study of 284 ICU patients with COVID-19 found a 33% incidence of VAP, predominantly caused by Pseudomonas aeruginosa and Klebsiella spp., with significant antimicrobial resistance noted in these bacteria.
- Key risk factors for developing VAP included receiving blood transfusions and certain therapies, with higher VAP rates linked to orotracheal intubation compared to tracheostomy, although patient positioning and specific admission ratios did not correlate significantly with VAP incidence.
Risk and predictive factors of prolonged viral RNA shedding in upper respiratory specimens in a large cohort of COVID-19 patients admitted to an Italian reference hospital.
Annalisa Mondi Patrizia Lorenzini Concetta Castilletti Roberta Gagliardini Eleonora Lalle Maria Elena Lamanna
Int J Infect Dis
April 2021
Article Synopsis
- The study analyzed COVID-19 patients in a hospital in Italy to explore factors influencing prolonged SARS-CoV-2 RNA shedding and viral clearance.
- It found that patients with comorbidities, lymphopenia, or moderate/severe respiratory issues had lower chances of viral clearance, with a median viral shedding duration of 18 days.
- Achieving viral clearance significantly improved clinical recovery rates and reduced the risk of death or the need for mechanical ventilation, emphasizing the necessity for timely hospital admission for symptomatic patients.