Publications by authors named "Maria E Soto-Martin"
The Integrated Care for Older People (ICOPE) program is a healthcare pathway that uses a screening test for intrinsic capacity (IC) as its entry point. However, real-life data informing on how IC domains cluster and change over time, as well as their clinical utility, are lacking. Using primary healthcare screening data from more than 20,000 French adults 60 years of age or older, this study identified four clusters of IC impairment: 'Low impairment' (most prevalent), 'Cognition+Locomotion+Hearing+Vision', 'All IC impaired' and 'Psychology+Vitality+Vision'.
View Article and Find Full Text PDFBackground: The mechanisms linking mild behavioral impairment (MBI) and Alzheimer's disease (AD) have been insufficiently explored, with conflicting results regarding tau protein and few data on other metabolic markers. We aimed to evaluate the longitudinal association of the MBI domains and a spectrum of plasma biomarkers.
Methods: Our study is a secondary analysis of data from NOLAN.
Article Synopsis
- The INSPIRE ICOPE-CARE programme focuses on improving integrated care for older adults by implementing the ICOPE health-care guidelines in real clinical settings.
- A large-scale study was conducted in France, where over 10,000 participants aged 60 and above were screened for intrinsic capacity abnormalities using several digital tools and received training under the WHO ICOPE framework.
- Results showed that 94.3% of participants had positive findings related to their intrinsic health, with a significant follow-up rate of 70.4% after six months, indicating the programme's feasibility and effectiveness in identifying health issues in older adults.
Background: Patients with dementia due to neurodegenerative disease can have dementia-related psychosis. The effects of the oral 5-HT inverse agonist and antagonist pimavanserin on psychosis related to various causes of dementia are not clear.
Methods: We conducted a phase 3, double-blind, randomized, placebo-controlled discontinuation trial involving patients with psychosis related to Alzheimer's disease, Parkinson's disease dementia, dementia with Lewy bodies, frontotemporal dementia, or vascular dementia.
Objective: To investigate the cross-sectional associations between depression in people with dementia and both caregiver burden and quality of life in 8 European countries, and to test these associations compared with the presence of other neuropsychiatric symptoms.
Design: Cross-sectional study.
Setting And Participants: In total, 1223 dyads comprised of informal caregivers and people with dementia living in a community-dwelling setting, recruited from the Right Time Place Care study, a cohort survey from 8 European countries.
Purpose: To describe available and utilized formal care and service at home for persons with dementia, from diagnosis to end-of-life stage, in eight European countries.
Design: A descriptive cross-country design concerning eight European countries as a part of the European research project RightTimePlaceCare.
Methods: The research team in each country used a mapping system to collect country-specific information concerning dementia care and service system.