Undetectable pre-ablation thyroglobulin levels in patients with differentiated thyroid cancer: it is not always what it seems.

Objective: To establish the frequency of U Tg (undetectable pre-ablation thyroglobulin) in TgAb- negative patients and to evaluate the outcome in the follow-up.

Subjects And Methods: We retrospectively reviewed 335 patients' records. Twenty eight patients (9%) had U Tg.

Patients with familial non-medullary thyroid cancer have an outcome similar to that of patients with sporadic papillary thyroid tumors.

Objective: The purpose of this study was to determine whether familial non-medullary thyroid cancer (FNMTC) is more aggressive than sporadic thyroid cancer.

Subjects And Methods: We compared the clinical behavior and outcome of 16 subjects with FNMTC from 7 unrelated kindred with those observed in 160 subjects with sporadic PTC (SPTC) from our database.

Results: The only different baseline characteristics observed between both groups were: bilateral malignancy, 38% vs.

Protocol for thyroid remnant ablation after recombinant TSH in thyroid carcinoma.

In some countries, in order to perform rhTSH-aided thyroid remnant ablation (TRA) after surgery, it is generally necessary to confirm that thyroidectomy has been almost complete. Otherwise, the nuclear medicine specialist will not administer a high radioiodine dose because it might be hazardous due to the possibility of thyroid remnant actinic thyroiditis. Considering this, it would be necessary to use two rhTSH kits (one for diagnostic purposes and the other one to administer the 131I dose).