Publications by authors named "Maria E Pratikaki"
Article Synopsis
- The study investigates the relationship between coenzyme Q10 (CoQ10) levels and the severity of sepsis in critically ill patients admitted to the ICU.
- CoQ10 levels were significantly lower in ICU patients who developed sepsis compared to healthy individuals, and levels decreased even further during septic shock.
- The findings indicate that lower CoQ10 levels could be linked to mitochondrial dysfunction and may serve as a potential biomarker for assessing sepsis severity.
Objectives: To investigate the impact of early initiation of hydrocortisone therapy on the clinical course of septic shock and on cytokine release.
Design: Prospective study in patients with septic shock treated with low doses of hydrocortisone.
Setting: ICUs and general wards.