Synopsis of recent research by authors named "Maria E Jaime"
- Maria E Jaime's research primarily focuses on the interaction between intracellular pathogens, particularly Mycobacterium tuberculosis (M. tuberculosis), and the immune response mechanisms in human macrophages.
- One of her significant findings highlights the role of interferon-γ (IFN-γ) and interleukin-10 (IL-10) in modulating the processing of M. tuberculosis antigens within the phagosomes, which is crucial for effective immune recognition.
- The study suggests that these cytokines influence the formation of mycobacterial antigen-MHC class II complexes, impacting the subsequent trafficking of these complexes to the cell surface for immune presentation.
