Publications by authors named "Maria Drudi Francesco"
Objective: Human beta-defensin-3 (HBD-3) is an antimicrobial peptide which is up-regulated during inflammation. Based on the previously demonstrated capacity of technetium-99m ((99m)Tc) labelled HBD-3 of distinguishing infection from inflammation in rats, we have decided to collect information on the potential toxicity of the tracer in view of its possible use for imaging in humans.
Materials And Methods: Recombinant HBD-3 underwent labeling with (99m)Tc.
Article Synopsis
- Diagnosing vasculitis in the brain is really hard because there isn’t a reliable imaging test that can do it well.
- This study looked at whether a special brain imaging technique called SPECT can help doctors know which patients with vasculitis will respond to treatment and which won’t.
- The results showed that SPECT could help doctors identify patients who improve after treatment and those whose condition gets worse.