Cryptococcal meningoencephalitis in a patient with hyper immunoglobulin M (IgM) syndrome: a case report.

Background: Cryptococcal meningoencephalitis is an opportunistic infection that predominantly affects immunocompromised patients. Hyper immunoglobulin M syndrome is a primary immunodeficiency syndrome that increases susceptibility to several opportunistic infections. Here, we report a case of cryptococcal meningoencephalitis in the context of hyper immunoglobulin M syndrome, a situation that has been reported very few times and whose management is not clearly defined.

Aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs.

We describe a novel heterothallic species in Aspergillus section Fumigati, namely A. felis (neosartorya-morph) isolated from three host species with invasive aspergillosis including a human patient with chronic invasive pulmonary aspergillosis, domestic cats with invasive fungal rhinosinusitis and a dog with disseminated invasive aspergillosis. Disease in all host species was often refractory to aggressive antifungal therapeutic regimens.

Infective endocarditis due to Streptococcus gallolyticus associated with colonic displasia.

Streptococcus gallolyticus is a microorganism belonging to the Streptococcus bovis I group isolated in humans, bovines and equines pigeons, among other animals. Streptococcus bovis is a Streptococcus strain found in the rumen, and has been isolated in the milk of animals with mastitis. The authors describe a case of an adult immunocompetent patient with underlying valvular heart disease, with bacteraemia and infective endocarditis by Streptococcus gallolyticus, in whom adenomatous colonic polyps with dysplasia were identified.

Aspergillus viridinutans: an agent of adult chronic invasive aspergillosis.

In contrast with the common hematogenous dissemination of invasive aspergillosis (IA), we present case with a protracted course through anatomical planes in an immunocompromised adult male. The unusual clinical features and laboratory findings led to fungal genotyping and identification of the mold as Aspergillus viridinutans. It appears to be the first described case of IA caused by this agent in an adult patient.

Streptococcus pneumoniae - caused CAP in hospitalised patients: mortality predictors.

Probably the most important decision in the management of Community-Acquired Pneumonia (CAP) is patient site of care. Patients with Streptococcus pneumoniae-caused CAP admitted to our hospital between 1st January and 31st December 2006 were retrospectively analysed. Samples of blood, sputum, bronchial and bronchoalveolar lavage and urine were collected for microbiological testing using standard culture techniques and urine antigen detection.