Publications by authors named "Maria Dolores Mansilla"
Front Immunol
November 2024
Article Synopsis
- A study on 173 female patients with recurrent reproductive failure (RRF) found a notably higher prevalence of HLA genes associated with celiac disease (CD) and non-celiac gluten sensitivity (NCGS), compared to the general population (69% vs. 35%-40%).
- Only a small percentage (2.3%) of the patients were diagnosed with CD, but those with HLA genetic susceptibility showed a significant link to higher rates of hypothyroidism (48.7% vs. 26.92%).
- Patients with both HLA susceptibility and thyroid disease had better pregnancy outcomes when on a gluten-free diet and using levothyroxine, indicating potential benefits of these interventions for reproductive success.
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