Association between clinical and IVF laboratory parameters and miscarriage after single euploid embryo transfers.

Background: The goal of this study was to investigate which factors, excluding embryo aneuploidies, are associated with miscarriage in patients who have undergone a single euploid blastocyst transfer.

Methods: Retrospective, observational and multicenter study with 2832 patients undergoing preimplantational genetic testing for aneuploidies (PGT-A) due to repeated implantation failure, recurrent pregnancy loss, advanced maternal age or severe male factor were transferred one single euploid embryo.

Results: One of the main findings was a significant relationship between body mass index (BMI) and miscarriage rates (13.

Extracellular vesicles as potential tools for regenerative therapy.

Small extracellular vesicles released by fibroblasts from young human donors diminish lipid peroxidation in senescent cells and in different old mice organs due to their enrichment in Glutathione-S-transferase Mu lipid antioxidant activity.

Type of chromosome abnormality affects embryo morphology dynamics.

Objective: To study the differences in the cleavage time between types of embryo chromosomal abnormalities and elaborate algorithm to exclude aneuploid embryos according to the likelihood to be euploid.

Design: Retrospective cohort study.

Setting: University affiliated private center.

Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetics analysis.

Objective: To study the differences in the cleavage time between chromosomally normal and abnormal embryos and to elaborate an algorithm to increase the probability of noninvasively selecting chromosomally normal embryos.

Design: Retrospective cohort study.

Setting: University-affiliated infertility center.

Corynebacterium striatum: an emerging nosocomial drug-resistant endocardial pathogen.

Endocarditis due to Corynebacterium striatum has been rarely reported. A 78-year-old patient developed pacemaker endocarditis caused by multidrug-resistant C. striatum, complicated by vertebral osteomyelitis and epidural abscess.