Publications by authors named "Maria Del Carmen Garcia de Leon"

Entamoeba histolytica calreticulin (EhCRT) is remarkably immunogenic in humans (90-100% of invasive amoebiasis patients). Nevertheless, the study of calreticulin in this protozoan is still in its early stages. The exact location, biological functions, and its role in pathogenesis are yet to be fully understood.

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Article Synopsis
  • The study examined the presence of senescent cells in the livers of five young children undergoing liver transplantation due to severe liver diseases like tyrosinemia and biliary atresia.
  • Results showed positive indicators of cellular senescence, such as SA-betagal activity, predominantly in the bile ducts and liver cells, especially in cases with cirrhosis and ductular transformations in fulminant hepatitis.
  • The findings suggest that cellular senescence in these livers reflects damage from disease rather than being an age-related process, indicating a need for further research on its links to disease progression.
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The frequency of Entamoeba histolytica and Entamoeba dispar infection was analyzed in a rural community in the state of Morelos, Mexico, using polymerase chain reaction (PCR). Sociodemographic variables as risk factors for the infection were assessed. Results highlighted the number of individuals with intestinal parasites (43.

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The frequency of Entamoeba histolytica and Entamoeba dispar infection was analyzed in a rural community in the state of Morelos, Mexico, through PCR technique by using specie specific primer. The E. histolytica specie was detected in 33 of 290 analyzed stool samples (11.

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Amebic cysteine protease 2 (EhCP2) was purified from ethyl ether extracts of axenically grown trophozoites of Entamoeba histolytica strain HM1-IMSS. The purification procedure involved molecular filtration and electroelution. Sequence analysis of the purified product revealed EhCP2 and ubiquitin(s).

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