Publications by authors named "Maria Dal Canto"

Article Synopsis
  • Clinical embryologists in Europe work in various roles within Medically Assisted Reproduction (MAR) centres but lack a standardized educational pathway.* -
  • In Italy, these professionals must complete a 3-4 year unpaid postgraduate specialization in fields like Genetics, Microbiology, Clinical Pathology, or Nutrition, with limited access to such programs.* -
  • The reliance on senior colleagues for training and the lack of uniformity in training curricula across Europe complicate recruitment and educational consistency for clinical embryologists.*
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Research Question: What is the intra- and inter-centre reliability in embryo grading performed according to the Istanbul Consensus across several IVF clinics?

Design: Forty Day 3 embryos and 40 blastocysts were photographed on three focal planes. Senior and junior embryologists from 65 clinics were invited to grade them according to the Istanbul Consensus (Study Phase I). All participants then attended interactive training where a panel of experts graded the same embryos (Study Phase II).

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Context: Human granulosa cells (GC) acquire LH receptor (LHR) expression during the follicular phase of the menstrual cycle. Currently, the precise follicular stage is unknown, and specific roles of LH in the follicular development are not fully understood.

Objective: Our objective was to measure LHR gene expression on GC and cumulus cells (CC) from normal human follicles with diameters form 3-20 mm.

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Oocyte selection with the highest competence is a major goal in IVF. Several studies demonstrated that non-classical HLA class I HLA-G molecule modulation creates a tolerogenic microenvironment at the feto-maternal interface and is implicated in embryo implantation. This study investigated if soluble HLA-G molecules producted by the cumulus-oocyte complex (COC) are markers of oocyte maturation.

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