Publications by authors named "Maria Cristina Visperas"
Article Synopsis
- The study investigates how the in vitro differentiation potential of human neural stem cells (hNSCs) relates to their ability to successfully migrate and engraft in vivo after transplantation into the brain of chicken embryos.
- Researchers cultured hNSCs in different concentrations of fetal bovine serum (0%, 0.1%, and 0.2%) and discovered that those grown in serum-free conditions showed successful in vivo engraftment, while those in higher serum concentrations did not.
- The findings indicate that traditional in vitro assays may not accurately predict the behavior of NSCs post-transplantation, pointing to a need for better methods to evaluate their potential for therapeutic use.
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