Publications by authors named "Maria Cristina Miranda de Araujo Correia"
Article Synopsis
- * Researchers isolated and sequenced HBCs and CTBs from placentae of women across different COVID-19 infection stages, discovering significant differences in gene expression when compared to unexposed controls, especially highlighting the second trimester as most affected.
- * Findings indicate that about 1,696 differentially expressed genes (DEGs) related to immune response and host defense mechanisms were identified in the second trimester, with implications for understanding the placenta's role during maternal infections.
Unlabelled: Understanding how some HIV-infected cells resist the cytotoxicity of HIV replication is crucial to enabling HIV cure efforts. HIV killing of CD4 T cells that replicate HIV can involve HIV protease-mediated cleavage of procaspase 8 to generate a fragment (Casp8p41) that directly binds and activates the mitochondrial proapoptotic protein BAK. Here, we demonstrate that Casp8p41 also binds with nanomolar affinity to the antiapoptotic protein Bcl-2, which sequesters Casp8p41 and prevents apoptosis.
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