Evaluation of HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1 polymorphisms associated with prostate cancer in samples of patients from HUPE-UERJ.

Purpose: Prostate cancer (PCa) is the leading cause of death among men in 48 countries. Genetic alterations play a significant role in PCa carcinogenesis. For the hypothesis of this research, five unique polymorphisms (SNP) were investigated in different genes that showed to be associated in different ways with PCa: rs4430796, rs2735839, rs4792311, rs12329760, and rs28931588, respectively for the genes HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1.

Parameters of 2-Dimensional Perineal Ultrasonography Before and After Male Sling Procedure for Urinary Incontinence After Radical Prostatectomy.

Objective: To compare ultrasonographic patterns of 2-dimensional perineal ultrasonography in men in the preoperative and postoperative periods after transobturator sling deployment for the treatment of urinary incontinence after radical prostatectomy. Radiotherapy and radical prostatectomy are the primary treatments for localized prostate cancer. Studies comparing anatomic changes in men before and after radical prostatectomy based on perineal ultrasonography are scarce in the literature.

Treatment of post-prostate surgery urinary incontinence with the periurethral constrictor: a retrospective analysis.

Objectives: In this study, we present safety and efficacy data for a surgical alternative for the treatment of postprostate surgery urinary incontinence, based on the use of the periurethral constrictor, a two-part device--constrictor cuff and self-sealing valve with a tube--activated by injection of saline solution.

Methods: From May 2001 to October 2007, 30 patients with postprostate surgery urinary incontinence were submitted to implantation of the periurethral constrictor.

Results: The mean follow-up was 42.