Evolution of Angiogenic Factors in Pregnant Patients with Breast Cancer Treated with Chemotherapy.

Unlabelled: High prevalence of placental-derived complications, such as preeclampsia and intrauterine growth restriction, has been reported in women with breast cancer (BC) treated with chemotherapy during pregnancy (PBC-CHT).

Aim: To ascertain whether PBC-CHT is associated with an imbalance of angiogenic factors, surrogate markers for placental insufficiency, that could explain perinatal outcomes.

Methods: Prospective study between 2012 and 2016 in a single institution.

Escherichia coli early-onset sepsis: trends over two decades.

Unlabelled: Escherichia coli early-onset sepsis (EOS) is an important cause of mortality and morbidity in neonates, especially in preterm and very low birth weight (VLBW) newborns. The aim of our study was to evaluate potential changes in the clinical and microbiological characteristics of E. coli EOS in our setting.