Beyond visual acuity: Patient-relevant assessment measures of visual function in retinal diseases.

Purpose: To identify (PROs) and other clinical outcome measures (contrast sensitivity (CS), low-luminance visual acuity (LLVA) and reading acuity or reading speed (RA-RS)), relevant to patients with age-related macular degeneration (AMD) or diabetic retinopathy (DR), which would be recommended for use in clinical practice.

Methods: The , based on the synthesis of the scientific evidence and the collective judgment of an expert panel using the two-round Delphi method, was applied. The evidence synthesis was performed by searching for articles on outcome measures for AMD and/or DR published between 2005 and 2018 in English or Spanish.

Association between central retinal thickness and low luminance visual acuity in early age-related macular degeneration.

Purpose/aim: To examine whether central retinal thickness (CRT) is related to mesopic visual acuity (VA) and low luminance deficit (LLD, difference between photopic and mesopic VA) in eyes with early and intermediate age-related macular degeneration (AMD).

Materials And Methods: In a cross-sectional study, 50 pseudophakic subjects older than 63 years were divided into three groups (no AMD, early AMD and intermediate AMD). Spectral domain optical coherence tomography (SD-OCT) was used to measure CRT in the 1 mm-central-area.

Abdominal obesity linked to a longer cone-mediated dark-adaptation recovery time in healthy eyes.

Obesity has been associated with abnormal lipid metabolism and with tissue hypoxia. Human Bruch's membrane (BrM) lipid deposits have been proposed to create a diffusion barrier to metabolic exchange between the choroid and photoreceptors, delaying the regeneration of photopigments. The speed of retinal dark adaptation (DA) is dependent on the regeneration of these photopigments.

Macular Inner Retinal Layer Thickness in Relation to Photopic and Mesopic Contrast Sensitivity in Healthy Young and Older Subjects.

Purpose: To examine relationships between the thicknesses of ganglion cell (GC)-related macular layers and central photopic or mesopic contrast sensitivity (CS) in healthy eyes.

Methods: Measurements were made in 38 young and 38 older healthy individuals. Total, inner, and outer retinal layer (IRL) thicknesses were measured in the macula region through spectral-domain optical coherence tomography (SD-OCT) across three subfields, or rings, centered at the fovea: central foveal, pericentral, and peripheral.

Macular Thickness and Mesopic Visual Acuity in Healthy Older Subjects.

Unlabelled: Purpose/Aim: Impaired mesopic visual acuity (VA) is a risk factor for incident early age-related macular degeneration (AMD) This study examines relationships between macular thickness measurements and photopic or mesopic VA in healthy eyes.

Materials And Methods: In 38 young and 39 older healthy individuals, total, inner, and outer retinal layer (IRL and ORL) thicknesses were measured in the macula region through spectral-domain optical coherence tomography (SD-OCT). Measurements were made across three subfields centered at the fovea: central foveal, pericentral, and peripheral.

Effects of Light Scatter and Blur on Low-Contrast Vision and Disk Halo Size.

Purpose: To investigate the individual effects of forward light scatter (FLS) and refractive blur on low-contrast vision and the size of the disk halo produced in response to an external glare source.

Methods: Monocular disk halo radius, high- and low-contrast distance visual acuity (HCVA, LCVA), and contrast sensitivity (CS) were determined in 25 eyes of 25 healthy subjects under normal, FLS, and blur conditions. FLS was induced using the filter Black ProMist 2 to simulate an early cataract.

Forward light scatter and visual acuity before and after intrastromal corneal ring segment implantation at different stages of keratoconus.

Purpose: To assess forward light scatter (stray light) before and after intrastromal corneal ring segment (ICRS) implantation at different stages of keratoconus and to examine correlation between postoperative stray light and visual acuity (VA).

Methods: In 27 eyes of 27 subjects with keratoconus, stray light was determined using the compensation comparison technique before and 6 months after ICRS implantation. Monocular corrected distance VA (CDVA) was measured using a high-contrast logMAR letter chart.

Changes in visual function under mesopic and photopic conditions after intrastromal corneal ring segment implantation for different stages of keratoconus.

Purpose: To analyze and compare the changes in visual function under mesopic and photopic conditions in different stages of keratoconus before and after Keraring intrastromal corneal ring segment (ICRS) implantation.

Setting: Clinico San Carlos Hospital and Faculty of Optics and Optometry, Complutense University, Madrid, Spain.

Design: Case series.

Effect of driver distraction and low alcohol concentrations on useful field of view and frequency-doubling technology perimetry.

Purpose: To investigate the effects of a mental psychometric task that simulates the distraction effect of a hands-free mobile phone and of low alcohol concentrations (0.3-0.5 g/l) on two tests: the useful field of view (UFOV) and frequency-doubling technology (FDT) perimetry.

Normal values for photopic and mesopic letter contrast sensitivity.

Purpose: The exponential increase of patients having refractive surgery has increased the number of patients with night vision disturbances, such as decreased contrast sensitivity. However, there are no standard contrast sensitivity scales in normal persons in the mesopic range. We describe Pelli-Robson contrast sensitivity under photopic and mesopic luminance conditions in a large Spanish population over a wide range of age groups to provide normal values.