Publications by authors named "Maria Christina L Machado"
Rationale: Normoxic heliox (mixture of 79% He and 21% O(2)) may enhance exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). It remains to be determined whether part of these beneficial effects could be ascribed to increased O(2) delivery (O(2)DEL) to locomotor muscles.
Objectives: To investigate the effects of heliox on peripheral O(2)DEL and utilization during exercise in moderate to severe COPD.
Rationale: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. The prevalence of COPD is rising among women and is approaching that of men, but it is not known if sex affects survival.
Objectives: To measure the survival differences between men and women with oxygen-dependent COPD.