Publications by authors named "Maria Cecilia da Matta Rivitti Machado"
Requirements for Brazilian Outpatient Centers of Excellence in Hidradenitis Suppurativa: Consensus Co-Creative Study.
Clin Cosmet Investig Dermatol
August 2023
Background: Hidradenitis suppurativa (HS) is a chronic skin condition. Its complexity and impact on patients highlight the need for multidisciplinary care that can address the physical, psychological, and social aspects. Centers of excellence can ideally provide the necessary infrastructure, resources, and expertise to effectively treat HS.
View Article and Find Full Text PDFA male infant presented with progressive jaundice immediately after birth. Fecal acholia and choluria associated with extensive bullous skin lesions in his trunk, abdomen, and upper and lower limbs developed during phototherapy. Several diagnostic hypotheses were presented, including neonatal porphyria, hemochromatosis, Alagille syndrome, and neonatal lupus.
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- Tuberous sclerosis complex (TSC) is a genetic disorder that affects various organs, characterized by the development of benign tumors (hamartomas) in areas such as the skin, brain, kidneys, and lungs.
- Diagnosis typically occurs within the first 15 months of life, often based on genetic mutations in tumor suppressor genes TSC1 and TSC2, alongside clinical indicators.
- Treatment focuses on symptom management and organ protection, with a multidisciplinary approach recommended for better patient outcomes.
Background: Scarring alopecias are classified into primary and secondary types according to the initial site of inflammation. In primary scarring alopecias, the hair follicle is the main target of destruction; the term secondary cicatricial alopecia implies that follicular destruction is not the primary pathologic event.
Aims: To review the histopathologic diagnoses of cases of cicatricial alopecia in order to classify them according to the North American Hair Research Society.
Article Synopsis
- A study analyzed 34 children under 16 with discoid lupus erythematosus over 9 years, finding that the condition is less common in this age group.
- The research revealed a higher female prevalence (2:1) and noted that 23.5% of children had an association with systemic lupus erythematosus, which is more than seen in adults.
- Children with systemic lupus erythematosus had a significantly higher rate of disseminated lesions (87.5%) compared to those without (34%), indicating potential worse outcomes, while histological results were similar to those in adults.
Juvenile hyaline fibromatosis and infantile systemic hyalinosis are rare autosomal recessive disorders of infancy and early childhood that are histologically characterized by deposition of hyaline material. The main clinical features are papulo-nodular skin lesions, gingival hypertrophy, joint contractures, and bone abnormalities. However, infantile systemic hyalinosis has a more severe clinical presentation, including visceral involvement and premature death.
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